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KMID : 0606620080040030109
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Korean Journal of Fetal Medicine
2008 Volume.4 No. 3 p.109 ~ p.207
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Management of Preterm Premature Rupture of Membrane
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Chung Ji-Youn
Moon Chong-Soo
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Abstract
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Preterm premature rupture of membranes (PPROM) is defined as spontaneous membrane rupture that occurs before the onset of labor, especially before 37 weeks. The incidence of PPROM has been reported to be approximately 3% of all pregnancies and is responsible for one third of all preterm births. Despite its prevalence, optimal management of PPROM remains largely undefined and lacks confirmity yet. PPROM is still assocaited with significant maternal, fetal and neonatal risk. Moreover, PPROM is primary contributor to perinatal morbidity and mortality because of its association with preterm delivery. Management of PPROM requires an accurate diagnosis as well as thoughtful evaluation of the risks and benefits of continued pregnancy versus expeditious delivery. An understanding of gestational age-dependent neonatal morbidity and mortality is the one of the most important in determining the potential benefits of conservative management of PPROM at any gestation. In this article, we review the pathophysiology and the recent developments of available management strategies in an effort to define current controversies in the management of PPROM.
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KEYWORD
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Preterm premature rupture of membranes, Prematurity, Perinatal morbidity
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